Best 1UP Weekend Betting Tips: Spurs Quest For Survival + More

It hasn’t been the best week for English teams. A lot had been said about all six Premier League representatives reaching the Round of 16 of the UEFA Champions League, and rightly so, but it came as a real shock to see every one of them fail to pick up a win this week. Surprisingly, it was Newcastle United, the least rated of the six, who came closest to a win, only to concede a 96th-minute equalizer to Barcelona. 

The second legs should still deliver plenty of drama, but for now the focus shifts back to the domestic scene as league football takes center stage again. Here’s what to watch out for:

• Total Odds: 177.65
• Booking Code: SC225S
• Acca Bonus: 20%

Our Picks:

Liverpool vs. Tottenham Hotspur

Things at Tottenham Hotspur have gone from bad to worse under Igor Tudor. Whatever the complete opposite of “new manager bounce” is, we’re looking at it. The Croatian coach inherited a struggling side and somehow made things even worse, losing all four matches since taking charge. The low point came in the 5–2 defeat to Atlético Madrid on Tuesday, where a surprise decision to drop Guglielmo Vicario for Antonín Kinský backfired badly. Kinský conceded three goals in just 18 minutes before being subbed off, and suddenly talk of Spurs being dragged into a relegation battle is no longer just banter.

To be fair, Tudor isn’t solely responsible for the mess. Far from it. Spurs haven’t won a Premier League game since December 28, long before he arrived, and the injury crisis that has plagued the club over the past two seasons has been brutal. Still, the numbers are worrying. Spurs have lost their last five league matches and are the only team without a Premier League win in 2026 so far.

Their trip to Anfield doesn’t make things easier. Liverpool may not be at their best this season and are outside the Champions League places, but they still dominate this fixture historically. The Reds have lost just one of their last 31 home league games against Spurs and have won four straight meetings since 2023. This is also the highest-scoring matchup in Premier League history with 209 goals.

There are also some interesting betting angles here. Liverpool games explode in the second half (their second halves have produced a league-high 59 goals) while Spurs matches often start fast. And then there’s Mohamed Salah, who loves facing Tottenham, with 16 career goals against them. If history is anything to go by, goals should definitely be on the menu again. 

Betting Tips: 

• Liverpool Win @1.36
• First Team Goal Liverpool - @1.34
• Mo Salah Anytime Scorer @2.30
• Over 2.5 Total Goals @1.48
• Higher Scoring Half - Second @1.96

Manchester United vs. Aston Villa 

Before their game against Newcastle, I boldly told the online sports betting community that I had a good read on Michael Carrick’s Manchester United and that their first defeat under him was going to be at St. James Park. That prediction proved right when, against all odds, William Osula scored a stoppage-time winner for the Magpies, who had been down to ten men for over 50 minutes.

Now, for United fans - and more importantly for you the readers - I’ve got great news: I believe Manchester United will bounce back here. If there’s one pattern with this United team, it’s that an embarrassing defeat usually wakes them up. After having 13 days to reflect on that loss, they should be far better prepared for this match, which also offers them a chance to create some distance from Aston Villa, who are just behind them in the Premier League table.

Another key factor is Villa’s Europa League tie on Thursday night. Facing a tough Lille side could take a lot out of them, and they’ll have only three days to recover before this game, compared to United’s 13 days of rest. The obvious pushback - and it’s a fair one - is that this season Villa have won seven of their eight domestic matches immediately after Europa League fixtures, which suggests fatigue hasn’t been an issue. Hard to argue with that record.

Still, at this stage of the campaign their squad is getting thin, no thanks to a few injuries. Their form over the last two months has also been poor, with just one win in their last seven matches across all competitions. The main issue has been their attack, which has produced only five goals during that run. Earlier in the season, the data showed that Unai Emery’s side were outperforming their expected goals (xG), a big reason behind their early success, but it also hinted that a regression might be coming. It looks like that moment has arrived.

As they often do, the Red Devils could still make things harder than necessary, but I’m backing Carrick’s side to get the job done here especially with Benjamin Šeško in fine scoring form and Bruno Fernandes creating chances for fun.

Betting Tips: 

• Bet Builder: Man Utd Win + Bruno Fernandes 1+ Assist @3.40 
• Man Utd 1UP @1.36
• Aston Villa Under 1.5 Goals @1.37

West Ham United vs. Manchester City

City find themselves in a tricky spot. Injuries to a few key players, a brutal run of fixtures, and the pressure of chasing an Arsenal side that has lost just three times in the last eight months have all put an unreal amount of pressure on Pep Guardiola's men. On top of that, they’re heading into the second leg of their Champions League tie against Real Madrid trailing 3–0 from the first leg.

In situations like this, rotation usually becomes crucial. But if you’re Pep Guardiola, how much can you really rotate with everything football has been throwing your way lately? My feeling is he might take a calculated gamble that sadly doesn’t quite work out. Turning around a 3–0 deficit against Real Madrid will demand fresh legs, and it’s hard to keep players fresh when you’re also trying to keep pace with Arsenal in the title race.

On the other hand, I’ve been quite impressed with West Ham United in their fight for survival, and my bet of the day is for them to go 1UP against the Citizens this weekend. On BetKing, that market is offering more than double your betting stake.

Betting Tip: 

• West Ham 1UP @2.23

Chelsea vs. Newcastle United 

The Blues suffered a strange defeat to holders Paris Saint-Germain on Wednesday. They showed real fight by coming from behind twice to level the game, which spoke to their resilience, but the final 15 minutes told a completely different story as they conceded three times and ended up collapsing.

Newcastle, meanwhile, put in a solid performance against Barcelona and were very close to pulling off an unlikely win. That should give them some confidence, but with injuries piling up, they’ll still have to make a few tough decisions in this game before their trip to Spain.

With both teams’ having must-win Champions League fixtures next week, this match could end up being more open than usual, which should mean an open, high-scoring game. 

Betting Tips: 

• Over 2.5 Goals @1.52
• Both Teams to Score @1.48

Bayer Leverkusen vs. Bayern Munich 

Once again, Champions League football will play a big role in this domestic game. Bayer Leverkusen got what I’d consider a positive result against Arsenal on Wednesday as they held the Gunners to a 1-1 draw. A corner-kick goal was scored, and surprisingly it was the Germans who got it, not the North London side, which says quite a lot about how the night unfolded.

Now they have to head to the Emirates Stadium hoping to pull off an upset, and that could mean putting their top-four battle on the back burner and resting a few players. That situation should play right into the hands of Bayern Munich, who have all but sealed a quarter-final qualification after a 6–1 first-leg win at Atalanta and will come into this game as overwhelming favourites. 

Betting Tips: 

• Bayern Over 1.5 Goals @1.40
• Bayern 1UP @1.23

Arsenal vs. Everton

The Gunners didn’t have their best night against Bayer Leverkusen, with star player Bukayo Saka even taken off just before the hour mark. Still, they avoided defeat, which should give them a bit of confidence heading into the weekend.

They now welcome Everton to the Emirates Stadium, a ground where they’ve lost just once all season. The Toffees have won three of their last five league games and won’t be easy opponents, but the Gunners are super focused on ending their 22-year wait for a Premier League title.

Mikel Arteta may have a Champions League game on the horizon, but he’ll have to go with his strongest lineup here, and that could be the key difference. It might not be the prettiest match, but the Gunners should still get the job done.

Betting Tips: 

• Arsenal 1UP @1.23
• Everton Under 1.5 Goals @1.11

Barcelona vs. Sevilla

Sevilla are in terrible form, with just one win in their last six games and defeats in most of their big matches this season. One result that really stands out, though, is their against Barcelona in early October. It was an end-to-end contest with 31 total shots and 15 on target, but Sevilla surprisingly came away 4–1 winners. Some Barcelona fans have pointed to the absence of attacking duo Raphinha and Lamine Yamal as a key reason for that result. To that I say “una no get shame? Using an 18-year-old as an excuse.” 

Once again, UCL football comes into the picture. Barcelona hosts Newcastle on Wednesday and will already have that in mind. Another thing to consider is Real Madrid who play 24 hours earlier, and that result could influence how the Catalans approach this game. A Madrid win that cuts the gap at the top to one point might see Hansi Flick take fewer risks, while a draw or loss for Los Blancos could allow Barcelona to ease off slightly. Either way, I actually expect Sevilla to avoid trailing at half-time, and on BetKing we’ve got the best odds for that.

Betting Tip: 

• First Half Double Chance: Sevilla Win or Draw @2.22

Como vs. AS Roma

In the race for Champions League football in Italy, it’s fourth vs fifth as Como take on AS Roma. Como have had some excellent Serie A results in recent weeks with three straight wins. Roma’s defeat at Genoa last weekend allowed Como to leapfrog them in the table, and the Giallorossi will be eager to reclaim that spot with both teams level on points. 

I’m not convinced that happens, though. Como have been very solid at home, losing just twice in 14 matches, while Roma have lost six of their 14 away games, with 57% of their league goals conceded coming on the road. I’ll stick with the data here - I think Cesc Fàbregas avoids defeat. Sure odds, if you ask me. 

Betting Tip: 

• Double Chance: Como Win or Draw @1.29

Inter vs. Atalanta

Inter’s loss in the derby last weekend blew the title race wide open, cutting their lead from 10 points to seven. It’s still a comfortable cushion, but anything other than a win this weekend and nerves could start creeping in. They couldn’t have asked for a better opponent, though: an Atalanta side that were just hammered 6–1 by Bayern Munich in front of their own fans. 

With three extra days of rest, I expect Inter to bounce back here and take the lead by half-time. Our HTUP market offers a good chance to cash in on that prediction. 

Betting Tip: 

• Inter HTUP @1.51

Lazio vs. Milan

Milan’s win against Inter was a massive confidence boost, and I expect them to ride that momentum as they head to Rome to face Lazio. Milan are the only side in Serie A yet to lose away from home this season and only Inter (33) have collected more points on the road than them (32). They also boast the best defense in the league, which could prove crucial against a Lazio team that have struggled in front of goal this season and currently rank 15th in attack. 

Betting Tips: 

• Milan 1UP @1.55
• Under 1.5 Lazio Goals @1.26

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